Human STARD5 activation kit by CRISPRa

SKU
GA112976
STARD5 CRISPRa kit - CRISPR gene activation of human StAR related lipid transfer domain containing 5
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol STARD5
Locus ID 80765
Components

GA112976G1, STARD5 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA112976G2, STARD5 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA112976G3, STARD5 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_030574, NM_181900, NR_135013
UniProt ID Q9NSY2
Synonyms MGC10327; StAR-related lipid transfer (START) domain containing 5; StAR-related lipid transfer protein 5; START domain containing 5
Summary Proteins containing a steroidogenic acute regulatory-related lipid transfer (START) domain are often involved in the trafficking of lipids and cholesterol between diverse intracellular membranes. This gene is a member of the StarD subfamily that encodes START-related lipid transfer proteins. The protein encoded by this gene is a cholesterol transporter and is also able to bind and transport other sterol-derived molecules related to the cholesterol/bile acid biosynthetic pathways such as 25-hydroxycholesterol. Its expression is upregulated during endoplasmic reticulum (ER) stress. The protein is thought to act as a cytosolic sterol transporter that moves cholesterol between intracellular membranes such as from the cytoplasm to the ER and from the ER to the Golgi apparatus. Alternative splicing of this gene produces multiple transcript variants. provided by RefSeq, Jan 2016
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Documents
Resources
Other Versions
SKU Description Size Price
KN402407 STARD5 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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