Human PRR7 activation kit by CRISPRa

SKU
GA112970
PRR7 CRISPRa kit - CRISPR gene activation of human proline rich 7, synaptic
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol PRR7
Locus ID 80758
Components

GA112970G1, PRR7 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA112970G2, PRR7 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA112970G3, PRR7 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001174101, NM_001174102, NM_030567
UniProt ID Q8TB68
Synonyms MGC10772
Summary Acts as a synapse-to-nucleus messenger to promote NMDA receptor-mediated excitotoxicity in neurons in a JUN-dependent manner (By similarity). Inhibits ubiquitination-mediated degradation and promotes phosphorylation and transcriptional activity of transcription factor JUN (PubMed:27458189). Might play a redundant role in the regulation of T cell receptor signaling (PubMed:21460222). Might promote apoptosis in T cells (PubMed:21460222).UniProtKB/Swiss-Prot Function
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Documents
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Other Versions
SKU Description Size Price
KN405637 PRR7 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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