Human MCAF2 (ATF7IP2) activation kit by CRISPRa

SKU
GA112809
ATF7IP2 CRISPRa kit - CRISPR gene activation of human activating transcription factor 7 interacting protein 2
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol ATF7IP2
Locus ID 80063
Components

GA112809G1, MCAF2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA112809G2, MCAF2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA112809G3, MCAF2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001256160, NM_024997, NR_045815, NR_045816, NM_001352120, NR_147927
UniProt ID Q5U623
Synonyms MCAF2
Summary Recruiter that couples transcriptional factors to general transcription apparatus and thereby modulates transcription regulation and chromatin formation. Can both act as an activator or a repressor depending on the context. Mediates MBD1-dependent transcriptional repression, probably by recruiting complexes containing SETDB1. The complex formed with MBD1 and SETDB1 represses transcription and probably couples DNA methylation and histone H3 'Lys-9' trimethylation (H3K9me3) activity (Probable).UniProtKB/Swiss-Prot Function
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Resources
Other Versions
SKU Description Size Price
KN406076 ATF7IP2 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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