Human FBXL18 activation kit by CRISPRa

SKU
GA112800
FBXL18 CRISPRa kit - CRISPR gene activation of human F-box and leucine rich repeat protein 18
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol FBXL18
Locus ID 80028
Components

GA112800G1, FBXL18 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA112800G2, FBXL18 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA112800G3, FBXL18 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_024963, NM_001321213, NM_001363441, NM_001363442, NM_001367780, NM_001367781
Synonyms Fbl18
Summary The protein encoded by this gene is a member of a family of proteins that contain an approximately 40-amino acid F-box motif. This motif is important for interaction with SKP1 and for targeting some proteins for degradation. The encoded protein has been shown to control the cellular level of FBXL7, a protein that induces mitotic arrest, by targeting it for polyubiquitylation and proteasomal degradation. Members of the F-box protein family, such as FBXL18, are characterized by an approximately 40-amino acid F-box motif. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains. provided by RefSeq, Mar 2016
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Documents
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Other Versions
SKU Description Size Price
KN420401 FBXL18 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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