Human WWC2 activation kit by CRISPRa

SKU GA112790

WWC2 CRISPRa kit - CRISPR gene activation of human WW and C2 domain containing 2

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: WWC2
• Locus ID: 80014
• Components:

  GA112790G1, WWC2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA112790G2, WWC2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA112790G3, WWC2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_024949
• UniProt ID: Q6AWC2
• Synonyms: BOMB
• Summary: This gene encodes a member of the WW-and-C2-domain-containing family of proteins. Members of this family have two N-terminal WW domains that mediate binding to target proteins harboring L/PPxY motifs, an internal C2 domain for membrane association, and C-terminal alpha protein kinase C binding sites and class III PDZ domain-interaction motifs. Proteins of this family are able to form homo- and heterodimers and to modulate hippo pathway signaling. [provided by RefSeq, Sep 2016]