Human PDZD3 activation kit by CRISPRa

SKU
GA112677
PDZD3 CRISPRa kit - CRISPR gene activation of human PDZ domain containing 3
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol PDZD3
Locus ID 79849
Components

GA112677G1, PDZD3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA112677G2, PDZD3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA112677G3, PDZD3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001168468, NM_024791, NR_033122
UniProt ID Q86UT5
Synonyms IKEPP; NHERF4; PDZK2
Summary Guanylyl cyclase C (GCC, or GUCY2C; MIM 601330) produces cGMP following the binding of either endogenous ligands or heat-stable enterotoxins secreted by E. coli and other enteric bacteria. Activation of GCC initiates a signaling cascade that leads to phosphorylation of the cystic fibrosis transmembrane conductance regulator (CFTR; MIM 602421), followed by a net efflux of ions and water into the intestinal lumen. IKEPP is a regulatory protein that associates with GCC and regulates the amount of cGMP produced following receptor stimulation (Scott et al., 2002 PubMed 11950846).supplied by OMIM, Mar 2008
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Documents
Resources
Other Versions
SKU Description Size Price
KN406415 PDZD3 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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