Human Multimerin 2 (MMRN2) activation kit by CRISPRa

SKU GA112644

MMRN2 CRISPRa kit - CRISPR gene activation of human multimerin 2

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: MMRN2
• Locus ID: 79812
• Components:

  GA112644G1, Multimerin 2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA112644G2, Multimerin 2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA112644G3, Multimerin 2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_024756
• UniProt ID: Q9H8L6
• Synonyms: EMILIN-3; EMILIN3; ENDOGLYX-1
• Summary: This gene encodes a protein belonging to the member of elastin microfibril interface-located (EMILIN) protein family. This family member is an extracellular matrix glycoprotein that can interfere with tumor angiogenesis and growth. It serves as a transforming growth factor beta antagonist and can interfere with the VEGF-A/VEGFR2 pathway. A related pseudogene has been identified on chromosome 6. [provided by RefSeq, Aug 2012]