Human MYH14 activation kit by CRISPRa

SKU GA112623

MYH14 CRISPRa kit - CRISPR gene activation of human myosin heavy chain 14

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: MYH14
• Locus ID: 79784
• Components:

  GA112623G1, MYH14 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA112623G2, MYH14 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA112623G3, MYH14 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_001077186, NM_001145809, NM_024729
• UniProt ID: Q7Z406
• Synonyms: DFNA4; DFNA4A; FP17425; MHC16; MYH17; myosin; NMHC-II-C; NMHC II-C; PNMHH
• Summary: This gene encodes a member of the myosin superfamily. The protein represents a conventional non-muscle myosin; it should not be confused with the unconventional myosin-14 (MYO14). Myosins are actin-dependent motor proteins with diverse functions including regulation of cytokinesis, cell motility, and cell polarity. Mutations in this gene result in one form of autosomal dominant hearing impairment. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]