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Human WDR59 activation kit by CRISPRa

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SKU
GA112580
WDR59 CRISPRa kit - CRISPR gene activation of human WD repeat domain 59
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA330823 Rabbit Polyclonal Anti-WDR59 Antibody
100 ul
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RC218128 WDR59 (Myc-DDK-tagged)-Human WD repeat domain 59 (WDR59)
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Other products for "WDR59"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol WDR59
Locus ID 79726
Components

GA112580G1, WDR59 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA112580G2, WDR59 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA112580G3, WDR59 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_024673, NM_030581, NM_001324171, NM_001324172
UniProt ID Q6PJI9
Synonyms FP977
Summary As a component of the GATOR subcomplex GATOR2, functions within the amino acid-sensing branch of the TORC1 signaling pathway. Indirectly activates mTORC1 and the TORC1 signaling pathway through the inhibition of the GATOR1 subcomplex (PubMed:23723238). It is negatively regulated by the upstream amino acid sensors SESN2 and CASTOR1 (PubMed:25457612, PubMed:27487210).UniProtKB/Swiss-Prot Function
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Documents
Resources
Other Versions
SKU Description Size Price
KN418128 WDR59 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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