Human AAGAB activation kit by CRISPRa

SKU GA112574

AAGAB CRISPRa kit - CRISPR gene activation of human alpha and gamma adaptin binding protein

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: AAGAB
• Locus ID: 79719
• Components:

  GA112574G1, AAGAB gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA112574G2, AAGAB gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA112574G3, AAGAB gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_001271885, NM_001271886, NM_024666
• UniProt ID: Q6PD74
• Synonyms: KPPP1; p34; PPKP1; PPKP1A
• Summary: The protein encoded by this gene interacts with the gamma-adaptin and alpha-adaptin subunits of complexes involved in clathrin-coated vesicle trafficking. Mutations in this gene are associated with type I punctate palmoplantar keratoderma. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Dec 2012]