Human SH3TC2 activation kit by CRISPRa

SKU GA112500

SH3TC2 CRISPRa kit - CRISPR gene activation of human SH3 domain and tetratricopeptide repeats 2

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: SH3TC2
• Locus ID: 79628
• Components:

  GA112500G1, SH3TC2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA112500G2, SH3TC2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA112500G3, SH3TC2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_024577
• UniProt ID: Q8TF17
• Synonyms: CMT4C; MNMN
• Summary: This gene encodes a protein with two N-terminal Src homology 3 (SH3) domains and 10 tetratricopeptide repeat (TPR) motifs, and is a member of a small gene family. The gene product has been proposed to be an adapter or docking molecule. Mutations in this gene result in autosomal recessive Charcot-Marie-Tooth disease type 4C, a childhood-onset neurodegenerative disease characterized by demyelination of motor and sensory neurons. [provided by RefSeq, Jul 2008]