Human GALNT14 activation kit by CRISPRa

SKU GA112495

GALNT14 CRISPRa kit - CRISPR gene activation of human polypeptide N-acetylgalactosaminyltransferase 14

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: GALNT14
• Locus ID: 79623
• Components:

  GA112495G1, GALNT14 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA112495G2, GALNT14 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA112495G3, GALNT14 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_001253826, NM_001253827, NM_001329095, NM_001329096, NM_001329097, NM_024572, NR_045602
• UniProt ID: Q96FL9
• Synonyms: GalNac-T10; GalNac-T14; GALNT15
• Summary: This gene encodes a Golgi protein which is a member of the polypeptide N-acetylgalactosaminyltransferase (ppGalNAc-Ts) protein family. These enzymes catalyze the transfer of N-acetyl-D-galactosamine (GalNAc) to the hydroxyl groups on serines and threonines in target peptides. The encoded protein has been shown to transfer GalNAc to large proteins like mucins. Alterations in this gene may play a role in cancer progression and response to chemotherapy. [provided by RefSeq, Jun 2016]