Human NOX5 activation kit by CRISPRa

SKU GA112437

NOX5 CRISPRa kit - CRISPR gene activation of human NADPH oxidase 5

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: NOX5
• Locus ID: 79400
• Components:

  GA112437G1, NOX5 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA112437G2, NOX5 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA112437G3, NOX5 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_001184779, NM_001184780, NM_024505, NR_033671, NR_033672
• UniProt ID: Q96PH1
• Synonyms: MGC149776; MGC149777
• Summary: This gene is predominantly expressed in the testis and lymphocyte-rich areas of spleen and lymph nodes. It encodes a calcium-dependen NADPH oxidase that generates superoxide, and functions as a calcium-dependent proton channel that may regulate redox-dependent processes in lymphocytes and spermatozoa. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Oct 2011]