Human EFHD2 activation kit by CRISPRa

SKU GA112408

EFHD2 CRISPRa kit - CRISPR gene activation of human EF-hand domain family member D2

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: EFHD2
• Locus ID: 79180
• Components:

  GA112408G1, EFHD2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA112408G2, EFHD2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA112408G3, EFHD2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_024329
• UniProt ID: Q96C19
• Synonyms: SWS1
• Summary: May regulate B-cell receptor (BCR)-induced immature and primary B-cell apoptosis. Plays a role as negative regulator of the canonical NF-kappa-B-activating branch. Controls spontaneous apoptosis through the regulation of BCL2L1 abundance.[UniProtKB/Swiss-Prot Function]