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Human CENPM activation kit by CRISPRa

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SKU
GA112314
CENPM CRISPRa kit - CRISPR gene activation of human centromere protein M
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

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100 ul
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RC201047 CENPM (Myc-DDK-tagged)-Human centromere protein M (CENPM), transcript variant 1
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Other products for "CENPM"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol CENPM
Locus ID 79019
Components

GA112314G1, CENPM gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA112314G2, CENPM gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA112314G3, CENPM gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001002876, NM_001110215, NM_001304370, NM_001304371, NM_001304372, NM_001304373, NM_024053
UniProt ID Q9NSP4
Synonyms C22orf18; CENP-M; PANE1
Summary The protein encoded by this gene is an inner protein of the kinetochore, the multi-protein complex that binds spindle microtubules to regulate chromosome segregation during cell division. It belongs to the constitutive centromere-associated network protein group, whose members interact with outer kinetochore proteins and help to maintain centromere identity at each cell division cycle. The protein is structurally related to GTPases but cannot bind guanosine triphosphate. A point mutation that affects interaction with another constitutive centromere-associated network protein, CENP-I, impairs kinetochore assembly and chromosome alignment, suggesting that it is required for kinetochore formation. Alternative splicing results in multiple transcript variants. provided by RefSeq, Jan 2015
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Documents
Resources
Other Versions
SKU Description Size Price
KN401047 CENPM - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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