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Human VKORC1 activation kit by CRISPRa

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SKU
GA112301
VKORC1 CRISPRa kit - CRISPR gene activation of human vitamin K epoxide reductase complex subunit 1
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA320006 Rabbit Polyclonal VKORC1 Antibody
100 ug
$640.00
RC202639 VKORC1 (Myc-DDK-tagged)-Human vitamin K epoxide reductase complex, subunit 1 (VKORC1), transcript variant 1
10 ug
$150.00

Other products for "VKORC1"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol VKORC1
Locus ID 79001
Components

GA112301G1, VKORC1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA112301G2, VKORC1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA112301G3, VKORC1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001311311, NM_024006, NM_206824
UniProt ID Q9BQB6
Synonyms EDTP308; MST134; MST576; VKCFD2; VKOR
Summary This gene encodes the catalytic subunit of the vitamin K epoxide reductase complex, which is responsible for the reduction of inactive vitamin K 2,3-epoxide to active vitamin K in the endoplasmic reticulum membrane. Vitamin K is a required co-factor for carboxylation of glutamic acid residues by vitamin K-dependent gamma-carboxylase in blood-clotting enzymes. Allelic variation in this gene is associated with vitamin k-dependent clotting factors combined deficiency of 2, and increased resistance or sensitivity to warfarin, an inhibitor of vitamin K epoxide reductase. Pseudogenes of this gene are located on chromosomes 1 and X. Alternative splicing results in multiple transcript variants. provided by RefSeq, Aug 2015
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Documents
Resources
Other Versions
SKU Description Size Price
KN402639 VKORC1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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