Human MPPE1 activation kit by CRISPRa

SKU GA112253

MPPE1 CRISPRa kit - CRISPR gene activation of human metallophosphoesterase 1

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: MPPE1
• Locus ID: 65258
• Components:

  GA112253G1, MPPE1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA112253G2, MPPE1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA112253G3, MPPE1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_001242904, NM_001319154, NM_001330563, NM_023075, NM_138608, NR_040241, NR_040242, NR_040243
• UniProt ID: Q53F39
• Synonyms: PGAP5
• Summary: Metallophosphoesterase required for transport of GPI-anchor proteins from the endoplasmic reticulum to the Golgi. Acts in lipid remodeling steps of GPI-anchor maturation by mediating the removal of a side-chain ethanolamine-phosphate (EtNP) from the second Man (Man2) of the GPI intermediate, an essential step for efficient transport of GPI-anchor proteins.[UniProtKB/Swiss-Prot Function]