Human CYP3A43 activation kit by CRISPRa

SKU GA112162

CYP3A43 CRISPRa kit - CRISPR gene activation of human cytochrome P450 family 3 subfamily A member 43

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: CYP3A43
• Locus ID: 64816
• Components:

  GA112162G1, CYP3A43 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA112162G2, CYP3A43 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA112162G3, CYP3A43 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_001278921, NM_022820, NM_057095, NM_057096, NR_103868, NR_103869
• UniProt ID: Q9HB55
• Summary: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The encoded protein has a low level of testosterone hydroxylase activity, and may play a role in aging mechanisms and cancer progression. This gene is part of a cluster of cytochrome P450 genes on chromosome 7q21.1. Alternate splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2013]