Human NMNAT1 activation kit by CRISPRa

SKU
GA112159
NMNAT1 CRISPRa kit - CRISPR gene activation of human nicotinamide nucleotide adenylyltransferase 1
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol NMNAT1
Locus ID 64802
Components

GA112159G1, NMNAT1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA112159G2, NMNAT1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA112159G3, NMNAT1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001297778, NM_001297779, NM_022787
UniProt ID Q9HAN9
Synonyms LCA9; NMNAT; PNAT1
Summary This gene encodes an enzyme which catalyzes a key step in the biosynthesis of nicotinamide adenine dinucleotide (NAD). The encoded enzyme is one of several nicotinamide nucleotide adenylyltransferases, and is specifically localized to the cell nucleus. Activity of this protein leads to the activation of a nuclear deacetylase that functions in the protection of damaged neurons. Mutations in this gene have been associated with Leber congenital amaurosis 9. Alternative splicing results in multiple transcript variants. Pseudogenes of this gene are located on chromosomes 1, 3, 4, 14, and 15. provided by RefSeq, Jul 2014
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Documents
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Other Versions
SKU Description Size Price
KN404825 NMNAT1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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