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Human CSN7b (COPS7B) activation kit by CRISPRa

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SKU
GA112107
COPS7B CRISPRa kit - CRISPR gene activation of human COP9 signalosome subunit 7B
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA362465 COPS7B Antibody - middle region
100 ul
$585.00
RC221465 COPS7B (Myc-DDK-tagged)-Human COP9 constitutive photomorphogenic homolog subunit 7B (Arabidopsis) (COPS7B)
10 ug
$300.00

Other products for "COPS7B"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol COPS7B
Locus ID 64708
Components

GA112107G1, CSN7b gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA112107G2, CSN7b gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA112107G3, CSN7b gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001282949, NM_001282950, NM_001282951, NM_001282952, NM_001308381, NM_022730, NM_001369483
UniProt ID Q9H9Q2
Synonyms CSN7B; SGN7b
Summary Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, JUN, I-kappa-B-alpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively.UniProtKB/Swiss-Prot Function
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Documents
Resources
Other Versions
SKU Description Size Price
KN421465 COPS7B - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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