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Human ZDHHC6 activation kit by CRISPRa

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SKU
GA112079
ZDHHC6 CRISPRa kit - CRISPR gene activation of human zinc finger DHHC-type containing 6
  $1,657.00
4 Weeks*

Frequently Bought Together (1)

RC215066 ZDHHC6 (Myc-DDK-tagged)-Human zinc finger, DHHC-type containing 6 (ZDHHC6)
10 ug
$457.00

Other products for "ZDHHC6"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol ZDHHC6
Locus ID 64429
Components

GA112079G1, ZDHHC6 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA112079G2, ZDHHC6 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA112079G3, ZDHHC6 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001303134, NM_022494, NM_001351082, NM_001351083, NM_001351084, NM_001351085, NM_001351086, NR_147045, NM_001363544
UniProt ID Q9H6R6
Synonyms DHHC-6; ZNF376
Summary Endoplasmic reticulum palmitoyl acyltransferase that mediates palmitoylation of proteins such as AMFR, CALX, ITPR1 and TFRC (PubMed:22314232, PubMed:22728137, PubMed:25368151, PubMed:28826475). Palmitoylates calnexin (CALX), which is required for its association with the ribosome-translocon complex and efficient folding of glycosylated proteins (PubMed:22314232). Mediates palmitoylation of AMFR, promoting AMFR distribution to the peripheral endoplasmic reticulum (PubMed:22728137). Together with SELENOK, palmitoylates ITPR1 in immune cells, leading to regulate ITPR1 stability and function (PubMed:25368151).UniProtKB/Swiss-Prot Function
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Documents
Resources
Other Versions
SKU Description Size Price
KN415066 ZDHHC6 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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