Human NXN activation kit by CRISPRa

SKU GA112047

NXN CRISPRa kit - CRISPR gene activation of human nucleoredoxin

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: NXN
• Locus ID: 64359
• Components:

  GA112047G1, NXN gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA112047G2, NXN gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA112047G3, NXN gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_001205319, NM_022463
• UniProt ID: Q6DKJ4
• Synonyms: NRX; TRG-4
• Summary: This gene encodes a member of the thioredoxin superfamily, a group of small, multifunctional redox-active proteins. Members of this family are characterized by a conserved active motif called the thioredoxin fold that catalyzes disulfide bond formation and isomerization. The encoded protein acts a redox-dependent regulator of the Wnt signaling pathway and is involved in cell growth and differentiation. [provided by RefSeq, Sep 2015]