Human ERAP2 activation kit by CRISPRa

SKU GA112002

ERAP2 CRISPRa kit - CRISPR gene activation of human endoplasmic reticulum aminopeptidase 2

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: ERAP2
• Locus ID: 64167
• Components:

  GA112002G1, ERAP2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA112002G2, ERAP2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA112002G3, ERAP2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_001130140, NM_001329229, NM_001329233, NM_022350, NR_137637
• UniProt ID: Q6P179
• Synonyms: L-RAP; LRAP
• Summary: This gene encodes a zinc metalloaminopeptidase of the M1 protease family that resides in the endoplasmic reticulum and functions in N-terminal trimming antigenic epitopes for presentation by major histocompatibility complex (MHC) class I molecules. Certain mutations in this gene are associated with the inflammatory arthritis syndrome ankylosing spondylitis and pre-eclampsia. This gene is located adjacent to a closely related aminopeptidase gene on chromosome 5. [provided by RefSeq, Jul 2016]