Human XYLT2 activation kit by CRISPRa

SKU
GA111994
XYLT2 CRISPRa kit - CRISPR gene activation of human xylosyltransferase 2
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol XYLT2
Locus ID 64132
Components

GA111994G1, XYLT2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA111994G2, XYLT2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA111994G3, XYLT2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_022167, NR_110010
UniProt ID Q9H1B5
Synonyms PXYLT2; SOS; XT-II; XT2; xylT-II
Summary The protein encoded by this gene is an isoform of xylosyltransferase, which belongs to a family of glycosyltransferases. This enzyme transfers xylose from UDP-xylose to specific serine residues of the core protein and initiates the biosynthesis of glycosaminoglycan chains in proteoglycans including chondroitin sulfate, heparan sulfate, heparin and dermatan sulfate. The enzyme activity, which is increased in scleroderma patients, is a diagnostic marker for the determination of sclerotic activity in systemic sclerosis. Alternatively spliced transcript variants have been found for this gene. provided by RefSeq, Dec 2013
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Documents
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Other Versions
SKU Description Size Price
KN408572 XYLT2 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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