Human SLC5A7 activation kit by CRISPRa

SKU
GA111851
SLC5A7 CRISPRa kit - CRISPR gene activation of human solute carrier family 5 member 7
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol SLC5A7
Locus ID 60482
Components

GA111851G1, SLC5A7 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA111851G2, SLC5A7 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA111851G3, SLC5A7 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001305005, NM_001305006, NM_001305007, NM_021815
UniProt ID Q9GZV3
Synonyms CHT; CHT1; hCHT; HMN7A
Summary This gene encodes a sodium ion- and chloride ion-dependent high-affinity transporter that mediates choline uptake for acetylcholine synthesis in cholinergic neurons. The protein transports choline from the extracellular space into presynaptic terminals for synthesis into acetylcholine. Increased choline uptake results from increased density of this protein in synaptosomal plasma membranes in response to depolarization of cholinergic terminals. Dysfunction of cholinergic signaling has been implicated in various disorders including depression, attention-deficit disorder, and schizophrenia. An allelic variant of this gene is associated with autosomal dominant distal hereditary motor neuronopathy type VIIA. Alternative splicing results in multiple transcript variants. provided by RefSeq, Jul 2015
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Documents
Resources
Other Versions
SKU Description Size Price
KN424138 SLC5A7 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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