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Human ALOXE3 activation kit by CRISPRa

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SKU
GA111830
ALOXE3 CRISPRa kit - CRISPR gene activation of human arachidonate lipoxygenase 3
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA308006 Rabbit Polyclonal antibody to ALOXE3 (arachidonate lipoxygenase 3)
100 ul
$665.00
RC212945 ALOXE3 (Myc-DDK-tagged)-Human arachidonate lipoxygenase 3 (ALOXE3), transcript variant 2
10 ug
$976.00

Other products for "ALOXE3"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol ALOXE3
Locus ID 59344
Components

GA111830G1, ALOXE3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA111830G2, ALOXE3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA111830G3, ALOXE3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001165960, NM_021628, NM_001369446
UniProt ID Q9BYJ1
Synonyms ARCI3; E-LOX; eLOX-3; eLOX3
Summary This gene is a member of the lipoxygenase family, which are catabolized by arachidonic acid-derived compounds. The encoded enzyme is a hydroperoxide isomerase that synthesizes a unique type of epoxy alcohol (8R-hydroxy-11R,12R-epoxyeicosa-5Z,9E,14Z-trienoic acid) from 12R-hydroperoxyeicosatetraenoic acid (12R-HPETE). This epoxy alcohol can activate the the nuclear receptor peroxisome proliferator-activated receptor alpha (PPARalpha), which is implicated in epidermal differentiation. Loss of function of the enzyme encoded by this gene results in ichthyosis, implicating the function of this gene in the differentiation of human skin. This gene is part of a cluster of lipoxygenase genes on 17p13.1. Mutations in this gene result in nonbullous congenital ichthyosiform erythroderma (NCIE). Multiple transcript variants encoding different isoforms have been found for this gene.provided by RefSeq, Sep 2009
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Documents
Resources
Other Versions
SKU Description Size Price
KN412945 ALOXE3 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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