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Human SINHCAF activation kit by CRISPRa

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SKU
GA111795
SINHCAF CRISPRa kit - CRISPR gene activation of human SIN3-HDAC complex associated factor
  $1,657.00
4 Weeks*

Frequently Bought Together (1)

RC200188 FAM60A (Myc-DDK-tagged)-Human family with sequence similarity 60, member A (FAM60A), transcript variant 2
10 ug
$300.00

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Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol SINHCAF
Locus ID 58516
Components

GA111795G1, SINHCAF gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA111795G2, SINHCAF gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA111795G3, SINHCAF gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001135811, NM_001135812, NM_021238
UniProt ID Q9NP50
Synonyms C12orf14; L4; TERA
Summary Subunit of the Sin3 deacetylase complex (Sin3/HDAC), this subunit is important for the repression of genes encoding components of the TGF-beta signaling pathway (PubMed:22865885, PubMed:22984288). Core component of a SIN3A complex (composed of at least SINHCAF, SIN3A, HDAC1, SAP30, RBBP4, OGT and TET1) present in embryonic stem (ES) cells. Promotes the stability of SIN3A and its presence on chromatin and is essential for maintaining the potential of ES cells to proliferate rapidly, while ensuring a short G1-phase of the cell cycle, thereby preventing premature lineage priming (By similarity).UniProtKB/Swiss-Prot Function
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Documents
Resources
Other Versions
SKU Description Size Price
KN400188 FAM60A - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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