Human DNASE2B activation kit by CRISPRa

SKU
GA111791
DNASE2B CRISPRa kit - CRISPR gene activation of human deoxyribonuclease 2 beta
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol DNASE2B
Locus ID 58511
Components

GA111791G1, DNASE2B gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA111791G2, DNASE2B gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA111791G3, DNASE2B gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_021233, NM_058248
UniProt ID Q8WZ79
Synonyms DLAD
Summary The protein encoded by this gene shares considerable sequence similarity to, and is structurally related to DNase II. The latter is a well characterized endonuclease that catalyzes DNA hydrolysis in the absence of divalent cations at acidic pH. Unlike DNase II which is ubiquitously expressed, expression of this gene product is restricted to the salivary gland and lungs. The gene has been localized to chromosome 1p22.3 adjacent (and in opposite orientation) to the uricase pseudogene. Two transcript variants encoding different isoforms have been described for this gene. provided by RefSeq, Jul 2008
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Other Versions
SKU Description Size Price
KN412192 DNASE2B - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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