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Human OSTC activation kit by CRISPRa

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SKU
GA111786
OSTC CRISPRa kit - CRISPR gene activation of human oligosaccharyltransferase complex non-catalytic subunit
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

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100 ul
$410.00
RC208881 OSTC (Myc-DDK-tagged)-Human oligosaccharyltransferase complex subunit (OSTC)
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Other products for "OSTC"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol OSTC
Locus ID 58505
Components

GA111786G1, OSTC gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA111786G2, OSTC gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA111786G3, OSTC gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001267817, NM_001267818, NM_021227
UniProt ID Q9NRP0
Synonyms DC2
Summary Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity. May be involved in N-glycosylation of APP (amyloid-beta precursor protein). Can modulate gamma-secretase cleavage of APP by enhancing endoprotelysis of PSEN1.UniProtKB/Swiss-Prot Function
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Documents
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Other Versions
SKU Description Size Price
KN408881 OSTC - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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