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Human SCUBE2 activation kit by CRISPRa

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SKU
GA111722
SCUBE2 CRISPRa kit - CRISPR gene activation of human signal peptide, CUB domain and EGF like domain containing 2
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

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100 ug
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RC230505L4V Lenti ORF particles, SCUBE2 (mGFP-tagged)-Human signal peptide, CUB domain, EGF-like 2 (SCUBE2), transcript variant 2, 200ul, >10^7 TU/mL
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Other products for "SCUBE2"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol SCUBE2
Locus ID 57758
Components

GA111722G1, SCUBE2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA111722G2, SCUBE2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA111722G3, SCUBE2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001170690, NM_020974, NM_001330199, NM_001367977
UniProt ID Q9NQ36
Synonyms CEGB1; CEGF1; CEGP1
Summary Lipid-binding protein required for SHH long-range signaling by binding to the dually lipid-modified SHH (ShhNp) and by promoting ShhNp mobilization, solubilization and release from the cell membrane (PubMed:22902404, PubMed:22677548). Acts by enhancing the proteolytic processing (shedding) of the lipid-modified N- and C- terminal of ShhNp at the cell surface (PubMed:24522195). Synergizes with DISP1 to increase SHH secretion (PubMed:22902404). Probable cell surface coreceptor for VEGFR2 involved in VEGFR2-mediated angiogenesis (PubMed:27834687).UniProtKB/Swiss-Prot Function
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Documents
Resources
Other Versions
SKU Description Size Price
KN424136 SCUBE2 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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