Human NCOA5 activation kit by CRISPRa

SKU GA111716

NCOA5 CRISPRa kit - CRISPR gene activation of human nuclear receptor coactivator 5

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: NCOA5
• Locus ID: 57727
• Components:

  GA111716G1, NCOA5 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA111716G2, NCOA5 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA111716G3, NCOA5 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_020967, NM_001348148, NM_001348149, NM_001348150, NM_001348151
• UniProt ID: Q9HCD5
• Synonyms: bA465L10.6; CIA
• Summary: This gene encodes a coregulator for the alpha and beta estrogen receptors and the orphan nuclear receptor NR1D2. The protein localizes to the nucleus, and is thought to have both coactivator and corepressor functions. Its interaction with nuclear receptors is independent of the AF2 domain on the receptors, which is known to regulate interaction with other coreceptors. Several alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2017]