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Human BEND3 activation kit by CRISPRa

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SKU
GA111674
BEND3 CRISPRa kit - CRISPR gene activation of human BEN domain containing 3
  $1,657.00
4 Weeks*

Frequently Bought Together (1)

RC215913 BEND3 (Myc-DDK-tagged)-Human BEN domain containing 3 (BEND3)
10 ug
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Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol BEND3
Locus ID 57673
Components

GA111674G1, BEND3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA111674G2, BEND3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA111674G3, BEND3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001080450, NM_001367314
UniProt ID Q5T5X7
Synonyms KIAA1553
Summary Transcriptional repressor which associates with the NoRC (nucleolar remodeling complex) complex and plays a key role in repressing rDNA transcription. The sumoylated form modulates the stability of the NoRC complex component BAZ2A/TIP5 by controlling its USP21-mediated deubiquitination (PubMed:21914818, PubMed:26100909). Binds to unmethylated major satellite DNA and is involved in the recruitment of the Polycomb repressive complex 2 (PRC2) to major satellites (By similarity). Stimulates the ERCC6L translocase and ATPase activities (PubMed:28977671).UniProtKB/Swiss-Prot Function
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Documents
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Other Versions
SKU Description Size Price
KN415913 BEND3 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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