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Human GRAMD1A activation kit by CRISPRa

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SKU
GA111662
GRAMD1A CRISPRa kit - CRISPR gene activation of human GRAM domain containing 1A
  $1,657.00
4 Weeks*

Frequently Bought Together (1)

RC226692 GRAMD1A (Myc-DDK-tagged)-Human GRAM domain containing 1A (GRAMD1A), transcript variant 2
10 ug
$653.00

Other products for "GRAMD1A"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol GRAMD1A
Locus ID 57655
Components

GA111662G1, GRAMD1A gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA111662G2, GRAMD1A gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA111662G3, GRAMD1A gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001136199, NM_001320034, NM_001320035, NM_001320036, NM_020895
UniProt ID Q96CP6
Synonyms KIAA1533
Summary Cholesterol transporter that mediates non-vesicular transport of cholesterol from the plasma membrane (PM) to the endoplasmic reticulum (ER) (By similarity). Contains unique domains for binding cholesterol and the PM, thereby serving as a molecular bridge for the transfer of cholesterol from the PM to the ER (By similarity). Plays a crucial role in cholesterol homeostasis and has the unique ability to localize to the PM based on the level of membrane cholesterol (By similarity). In lipid-poor conditions localizes to the ER membrane and in response to excess cholesterol in the PM is recruited to the endoplasmic reticulum-plasma membrane contact sites (EPCS) which is mediated by the GRAM domain (By similarity). At the EPCS, the sterol-binding VASt/ASTER domain binds to the cholesterol in the PM and facilitates its transfer from the PM to ER (By similarity). May play a role in tumor progression (By similarity).UniProtKB/Swiss-Prot Function
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Documents
Resources
Other Versions
SKU Description Size Price
KN404274 GRAMD1A - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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