Human MARCHF4 activation kit by CRISPRa

SKU
GA111601
MARCH4 CRISPRa kit - CRISPR gene activation of human membrane associated ring-CH-type finger 4
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol MARCHF4
Locus ID 57574
Components

GA111601G1, MARCHF4 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA111601G2, MARCHF4 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA111601G3, MARCHF4 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_020814
UniProt ID Q9P2E8
Synonyms MARCH-IV; RNF174
Summary MARCH4 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 6.3.2.19). MARCH enzymes add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments. MARCH4 reduces surface accumulation of several membrane glycoproteins by directing them to the endosomal compartment (Bartee et al., 2004 PubMed 14722266).supplied by OMIM, Apr 2010
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Documents
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Other Versions
SKU Description Size Price
KN412197 MARCH4 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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