Human NLN activation kit by CRISPRa

SKU GA111529

NLN CRISPRa kit - CRISPR gene activation of human neurolysin

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: NLN
• Locus ID: 57486
• Components:

  GA111529G1, NLN gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA111529G2, NLN gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA111529G3, NLN gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_020726
• UniProt ID: Q9BYT8
• Synonyms: AGTBP; EP24.16; MEP; MOP
• Summary: This gene encodes a member of the metallopeptidase M3 protein family that cleaves neurotensin at the Pro10-Tyr11 bond, leading to the formation of neurotensin(1-10) and neurotensin(11-13). The encoded protein is likely involved in the termination of the neurotensinergic signal in the central nervous system and in the gastrointestinal tract.[provided by RefSeq, Jun 2010]