OriGene Logo

Customer Login

Checkout as a new customer

Creating an account has many benefits:

  • See order and shipping status
  • Track order history
  • Check out faster
Create an Account

Human GRAMD1B activation kit by CRISPRa

Be the first to review this product
SKU
GA111521
GRAMD1B CRISPRa kit - CRISPR gene activation of human GRAM domain containing 1B
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA331820 Rabbit Polyclonal Anti-GRAMD1B Antibody
100 ul
$585.00
RC219269 GRAMD1B (Myc-DDK-tagged)-Human GRAM domain containing 1B (GRAMD1B)
10 ug
$676.00

Other products for "GRAMD1B"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol GRAMD1B
Locus ID 57476
Components

GA111521G1, GRAMD1B gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA111521G2, GRAMD1B gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA111521G3, GRAMD1B gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001286563, NM_001286564, NM_001330396, NM_020716, NM_001354837, NM_001367420, NM_001367421, NM_001367418, NM_001367419
UniProt ID Q3KR37
Summary Cholesterol transporter that mediates non-vesicular transport of cholesterol from the plasma membrane (PM) to the endoplasmic reticulum (ER) (By similarity). Contains unique domains for binding cholesterol and the PM, thereby serving as a molecular bridge for the transfer of cholesterol from the PM to the ER (By similarity). Plays a crucial role in cholesterol homeostasis in the adrenal gland and has the unique ability to localize to the PM based on the level of membrane cholesterol (By similarity). In lipid-poor conditions localizes to the ER membrane and in response to excess cholesterol in the PM is recruited to the endoplasmic reticulum-plasma membrane contact sites (EPCS) which is mediated by the GRAM domain (By similarity). At the EPCS, the sterol-binding VASt/ASTER domain binds to the cholesterol in the PM and facilitates its transfer from the PM to ER (By similarity).UniProtKB/Swiss-Prot Function
Reviews
Write Review
 
 
 
 
 

Be the first to review this product

Please note:
Only reviews with images are eligible for a $20/20€ Amazon gift card.
Reviews without images are eligible for a $10/10€ Amazon gift card.
For more details about the terms and conditions, please visit the promotion page.

Review image
Documents
Resources
Other Versions
SKU Description Size Price
KN219269 GRAMD1B - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN219269BN GRAMD1B - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN219269LP GRAMD1B - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN219269RB GRAMD1B - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN419269 GRAMD1B - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

file-alt Citations

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

Related Products