Human LYRM1 activation kit by CRISPRa
Specifications
| Product Data | |
| Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
|---|---|
| Target Symbol | LYRM1 |
| Locus ID | 57149 |
| Components |
GA111408G1, LYRM1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA111408G2, LYRM1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA111408G3, LYRM1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
| OTI Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
| Shipping | Ambient |
| Reference Data | |
| RefSeq | NM_001128301, NM_001128302, NM_001302835, NM_001302836, NM_020424, NR_126516, NR_126520, NR_126521, NR_126527, NR_126528, NM_001369632, NM_001369633, NM_001369635, NM_001369636, NM_001369638, NM_001369639, NM_001369641, NM_001369642, NM_001369644, NR_161425, NR_161426, NR_161429, NR_161430, NM_001369631, NM_001369634, NM_001369637, NM_001369645, NR_161427, NR_161431, NR_161432 |
| UniProt ID | O43325 |
| Synonyms | A211C6.1 |
| Summary | The protein encoded by this gene belongs to the mitochondrial leucine/tyrosine/arginine motif family of proteins. Proteins of this family are short polypeptides that contain a leucine/tyrosine/arginine motif near the N-terminus. This gene is widely expressed with high levels in omental adipose tissue of obese individuals. In adipose tissue, the protein is localized to the nucleus where it promotes preadipocyte proliferation and lowers the rate of apoptosis to regulate adipose tissue homeostasis. Overexpression of this gene in adipocytes causes abnormal mitochondrial morphology and mitochondrial dysfunction. Alternative splicing results in multiple transcript variants. provided by RefSeq, Nov 2014 |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| KN402041 | LYRM1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. | 1 kit |
$1,657.00
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Citations
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