Human PDSS2 activation kit by CRISPRa

SKU GA111376

PDSS2 CRISPRa kit - CRISPR gene activation of human decaprenyl diphosphate synthase subunit 2

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: PDSS2
• Locus ID: 57107
• Components:

  GA111376G1, PDSS2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA111376G2, PDSS2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA111376G3, PDSS2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_020381
• UniProt ID: Q86YH6
• Synonyms: bA59I9.3; C6orf210; COQ10D3; DLP1; hDLP1
• Summary: The protein encoded by this gene is an enzyme that synthesizes the prenyl side-chain of coenzyme Q, or ubiquinone, one of the key elements in the respiratory chain. The gene product catalyzes the formation of all trans-polyprenyl pyrophosphates from isopentyl diphosphate in the assembly of polyisoprenoid side chains, the first step in coenzyme Q biosynthesis. Defects in this gene are a cause of coenzyme Q10 deficiency.[provided by RefSeq, Oct 2009]