Human TIGAR activation kit by CRISPRa

SKU
GA111372
TIGAR CRISPRa kit - CRISPR gene activation of human TP53 induced glycolysis regulatory phosphatase
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol TIGAR
Locus ID 57103
Components

GA111372G1, TIGAR gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA111372G2, TIGAR gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA111372G3, TIGAR gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_020375
UniProt ID Q9NQ88
Synonyms C12orf5; FR2BP
Summary This gene is regulated as part of the p53 tumor suppressor pathway and encodes a protein with sequence similarity to the bisphosphate domain of the glycolytic enzyme that degrades fructose-2,6-bisphosphate. The protein functions by blocking glycolysis and directing the pathway into the pentose phosphate shunt. Expression of this protein also protects cells from DNA damaging reactive oxygen species and provides some protection from DNA damage-induced apoptosis. The 12p13.32 region that includes this gene is paralogous to the 11q13.3 region. provided by RefSeq, Jul 2008
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Documents
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Other Versions
SKU Description Size Price
KN404087 C12orf5 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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