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Human TWSG1 activation kit by CRISPRa

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SKU
GA111346
TWSG1 CRISPRa kit - CRISPR gene activation of human twisted gastrulation BMP signaling modulator 1
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

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RC202337 TWSG1 (Myc-DDK-tagged)-Human twisted gastrulation homolog 1 (Drosophila) (TWSG1)
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Other products for "TWSG1"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol TWSG1
Locus ID 57045
Components

GA111346G1, TWSG1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA111346G2, TWSG1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA111346G3, TWSG1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_020648
UniProt ID Q9GZX9
Synonyms TSG
Summary May be involved in dorsoventral axis formation. Seems to antagonize BMP signaling by forming ternary complexes with CHRD and BMPs, thereby preventing BMPs from binding to their receptors. In addition to the anti-BMP function, also has pro-BMP activity, partly mediated by cleavage and degradation of CHRD, which releases BMPs from ternary complexes. May be an important modulator of BMP-regulated cartilage development and chondrocyte differentiation. May play a role in thymocyte development (By similarity).UniProtKB/Swiss-Prot Function
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Documents
Resources
Other Versions
SKU Description Size Price
KN402337 TWSG1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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