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Human PRDM9 activation kit by CRISPRa

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SKU
GA111314
PRDM9 CRISPRa kit - CRISPR gene activation of human PR/SET domain 9
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

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RC218187 PRDM9 (Myc-DDK-tagged)-Human PR domain containing 9 (PRDM9)
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Other products for "PRDM9"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol PRDM9
Locus ID 56979
Components

GA111314G1, PRDM9 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA111314G2, PRDM9 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA111314G3, PRDM9 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_020227
UniProt ID Q9NQV7
Synonyms MEISETZ; MSBP3; PFM6; PRMD9; ZNF899
Summary The protein encoded by this gene is a zinc finger protein with histone methyltransferase activity that catalyzes histone H3 lysine 4 trimethylation (H3K4me3) during meiotic prophase. This protein contains multiple domains, including a Kruppel-associated box (KRAB) domain, an SSX repression domain (SSXRD), a PRD1-BF1 and RIZ homologous region, a subclass of SET (PR/SET) domain, and a tandem array of C2H2 zinc fingers. The zinc finger array recognizes a short sequence motif, leading to local H3K4me3, and meiotic recombination hotspot activity. The observed allelic variation alters the DNA-binding sequence specificity of the protein, resulting in distinct meiotic recombination hotspots amongst individuals and populations. Multiple alternate alleles of this gene have been described. provided by RefSeq, Jul 2015
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Documents
Resources
Other Versions
SKU Description Size Price
KN418187 PRDM9 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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