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Human PRDM8 activation kit by CRISPRa

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SKU
GA111313
PRDM8 CRISPRa kit - CRISPR gene activation of human PR/SET domain 8
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

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RC220345 PRDM8 (Myc-DDK-tagged)-Human PR domain containing 8 (PRDM8), transcript variant 1
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Other products for "PRDM8"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol PRDM8
Locus ID 56978
Components

GA111313G1, PRDM8 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA111313G2, PRDM8 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA111313G3, PRDM8 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001099403, NM_020226
UniProt ID Q9NQV8
Synonyms PFM5
Summary This gene encodes a protein that belongs to a conserved family of histone methyltransferases that predominantly act as negative regulators of transcription. The encoded protein contains an N-terminal Su(var)3-9, Enhancer-of-zeste, and Trithorax (SET) domain and a double zinc-finger domain. Knockout of this gene in mouse results in mistargeting by neurons of the dorsal telencephalon, abnormal itch-like behavior, and impaired differentiation of rod bipolar cells. In humans, the protein has been shown to interact with the phosphatase laforin and the ubiquitin ligase malin, which regulate glycogen construction in the cytoplasm. Alternative splicing results in multiple transcript variants. provided by RefSeq, Feb 2016
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Documents
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Other Versions
SKU Description Size Price
KN420345 PRDM8 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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