Human MDM1 activation kit by CRISPRa

SKU GA111243

MDM1 CRISPRa kit - CRISPR gene activation of human Mdm1 nuclear protein

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: MDM1
• Locus ID: 56890
• Components:

  GA111243G1, MDM1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA111243G2, MDM1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA111243G3, MDM1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_001205028, NM_001205029, NM_017440, NM_020128, NM_001354969, NM_001354970, NM_001354971, NM_001354972, NM_001354973, NM_001354974, NM_001368282
• UniProt ID: Q8TC05
• Synonyms: FLJ95264
• Summary: This gene encodes a microtubule-binding nuclear protein that localizes to the centrioles of dividing cells and differentiating multiciliated cells and negatively regulates centriole duplication. The encoded protein is closely associated with the centriole barrel, and resides in the centriole lumen. Naturally-occurring mutations in the orthologous mouse gene are associated with age-related retinal degeneration. [provided by RefSeq, Feb 2019]