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Human PCDHGB6 activation kit by CRISPRa

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SKU
GA111098
PCDHGB6 CRISPRa kit - CRISPR gene activation of human protocadherin gamma subfamily B, 6
  $1,657.00
4 Weeks*

Frequently Bought Together (1)

RC221985 PCDHGB6 (Myc-DDK-tagged)-Human protocadherin gamma subfamily B, 6 (PCDHGB6), transcript variant 2
10 ug
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Other products for "PCDHGB6"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol PCDHGB6
Locus ID 56100
Components

GA111098G1, PCDHGB6 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA111098G2, PCDHGB6 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA111098G3, PCDHGB6 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_018926, NM_032100
UniProt ID Q9Y5F9
Synonyms PCDH-GAMMA-B6
Summary This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes. provided by RefSeq, Jul 2008
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Documents
Resources
Other Versions
SKU Description Size Price
KN416903 PCDHGB6 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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