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Human DMAP1 activation kit by CRISPRa

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SKU
GA111065
DMAP1 CRISPRa kit - CRISPR gene activation of human DNA methyltransferase 1 associated protein 1
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

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Other products for "DMAP1"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol DMAP1
Locus ID 55929
Components

GA111065G1, DMAP1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA111065G2, DMAP1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA111065G3, DMAP1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001034023, NM_001034024, NM_019100
UniProt ID Q9NPF5
Synonyms DNMAP1; DNMTAP1; EAF2; MEAF2; SWC4
Summary This gene encodes a subunit of several, distinct complexes involved in the repression or activation of transcription. The encoded protein can independently repress transcription and is targeted to replication foci throughout S phase by interacting directly with the N-terminus of DNA methyltransferase 1. During late S phase, histone deacetylase 2 is added to this complex, providing a means to deacetylate histones in transcriptionally inactive heterochromatin following replication. The encoded protein is also a component of the nucleosome acetyltransferase of H4 complex and interacts with the transcriptional corepressor tumor susceptibility gene 101 and the pro-apoptotic death-associated protein 6, among others. Alternatively spliced transcript variants encoding the same protein have been described. provided by RefSeq, Jul 2008
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Documents
Resources
Other Versions
SKU Description Size Price
KN401071 DMAP1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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