Human DOK5 activation kit by CRISPRa

SKU
GA110994
DOK5 CRISPRa kit - CRISPR gene activation of human docking protein 5
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol DOK5
Locus ID 55816
Components

GA110994G1, DOK5 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA110994G2, DOK5 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA110994G3, DOK5 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001294161, NM_018431, NM_177959
UniProt ID Q9P104
Synonyms C20orf180; IRS-6; IRS6
Summary The protein encoded by this gene is a member of the DOK family of membrane proteins, which are adapter proteins involved in signal transduction. The encoded protein interacts with phosphorylated receptor tyrosine kinases to mediate neurite outgrowth and activation of the MAP kinase pathway. Unlike other DOK family proteins, this protein does not interact with RASGAP. This protein is up-regulated in patients with systemic sclerosis and is associated with fibrosis induced by insulin-like growth factor binding protein 5. Alternative splicing of this gene results in multiple transcript variants. provided by RefSeq, Jun 2014
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Documents
Resources
Other Versions
SKU Description Size Price
KN411718 DOK5 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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