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Human TDP1 activation kit by CRISPRa

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SKU
GA110958
TDP1 CRISPRa kit - CRISPR gene activation of human tyrosyl-DNA phosphodiesterase 1
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA503768 TDP1 mouse monoclonal antibody, clone OTI4H1 (formerly 4H1) 100 ul
$447.00
RC214927 TDP1 (Myc-DDK-tagged)-Human tyrosyl-DNA phosphodiesterase 1 (TDP1), transcript variant 1
10 ug
$566.00

Other products for "TDP1"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol TDP1
Locus ID 55775
Components

GA110958G1, TDP1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA110958G2, TDP1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA110958G3, TDP1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001008744, NM_001330205, NM_018319
UniProt ID Q9NUW8
Synonyms FLJ11090; MGC104252
Summary The protein encoded by this gene is involved in repairing stalled topoisomerase I-DNA complexes by catalyzing the hydrolysis of the phosphodiester bond between the tyrosine residue of topoisomerase I and the 3-prime phosphate of DNA. This protein may also remove glycolate from single-stranded DNA containing 3-prime phosphoglycolate, suggesting a role in repair of free-radical mediated DNA double-strand breaks. This gene is a member of the phospholipase D family and contains two PLD phosphodiesterase domains. Mutations in this gene are associated with the disease spinocerebellar ataxia with axonal neuropathy (SCAN1). provided by RefSeq, Aug 2016
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Other Versions
SKU Description Size Price
KN401888 TDP1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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