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Human ZCCHC8 activation kit by CRISPRa

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SKU
GA110809
ZCCHC8 CRISPRa kit - CRISPR gene activation of human zinc finger CCHC-type containing 8
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

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100 ul
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RC209528 ZCCHC8 (Myc-DDK-tagged)-Human zinc finger, CCHC domain containing 8 (ZCCHC8)
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Other products for "ZCCHC8"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol ZCCHC8
Locus ID 55596
Components

GA110809G1, ZCCHC8 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA110809G2, ZCCHC8 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA110809G3, ZCCHC8 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_017612, NM_001350935, NM_001350936, NM_001350937, NM_001350938
UniProt ID Q6NZY4
Synonyms DKFZp434E2220
Summary This gene encodes a scaffold protein which serves as an assessory factor to the nuclear RNA exosome complex. The encoded protein forms a trimeric human nuclear exosome targeting (NEXT) complex, together with hMTR4 and the RNA-binding factor RBM7 which promotes the exosomal degradation of non-coding promoter-upstream transcripts, enhancer RNAs and 3'-extended products of histone- and small nuclear RNA transcription. This complex is also thought to recruit the exosome to degrade intronic RNAs via its interaction with both the exosome and the spliceosome. It contains both an N-terminal zinc-knuckle domain and a C-terminal proline-rich domain. provided by RefSeq, Apr 2017
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Documents
Resources
Other Versions
SKU Description Size Price
KN409528 ZCCHC8 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

file-alt Citations

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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