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Human TMEM100 activation kit by CRISPRa

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SKU
GA110661
TMEM100 CRISPRa kit - CRISPR gene activation of human transmembrane protein 100
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA500532 TMEM100 mouse monoclonal antibody, clone OTI10G3 (formerly 10G3) 100 ul
$447.00
RC203980 TMEM100 (Myc-DDK-tagged)-Human transmembrane protein 100 (TMEM100), transcript variant 2
10 ug
$150.00

Other products for "TMEM100"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol TMEM100
Locus ID 55273
Components

GA110661G1, TMEM100 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA110661G2, TMEM100 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA110661G3, TMEM100 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001099640, NM_018286
UniProt ID Q9NV29
Synonyms FLJ10970; FLJ37856
Summary Plays a role during embryonic arterial endothelium differentiation and vascular morphogenesis through the ACVRL1 receptor-dependent signaling pathway upon stimulation by bone morphogenetic proteins, such as GDF2/BMP9 and BMP10. Involved in the regulation of nociception, acting as a modulator of the interaction between TRPA1 and TRPV1, two molecular sensors and mediators of pain signals in dorsal root ganglia (DRG) neurons. Mechanistically, it weakens their interaction, thereby releasing the inhibition of TRPA1 by TRPV1 and increasing the single-channel open probability of the TRPA1-TRPV1 complex.UniProtKB/Swiss-Prot Function
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Documents
Resources
Other Versions
SKU Description Size Price
KN403980 TMEM100 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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