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Human BBS7 activation kit by CRISPRa

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SKU
GA110610
BBS7 CRISPRa kit - CRISPR gene activation of human Bardet-Biedl syndrome 7
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

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100 ul
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RC207504 BBS7 (Myc-DDK-tagged)-Human Bardet-Biedl syndrome 7 (BBS7), transcript variant 2
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Other products for "BBS7"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol BBS7
Locus ID 55212
Components

GA110610G1, BBS7 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA110610G2, BBS7 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA110610G3, BBS7 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_018190, NM_176824
UniProt ID Q8IWZ6
Synonyms BBS2L1
Summary This gene encodes one of eight proteins that form the BBSome complex containing BBS1, BBS2, BBS4, BBS5, BBS7, BBS8, BBS9 and BBIP10. The BBSome complex is believed to recruit Rab8(GTP) to the primary cilium and promote ciliogenesis. The BBSome complex assembly is mediated by a complex composed of three chaperonin-like BBS proteins (BBS6, BBS10, and BBS12) and CCT/TRiC family chaperonins. Mutations in this gene are implicated in Bardet-Biedl syndrome, a genetic disorder whose symptoms include obesity, retinal degeneration, polydactyly and nephropathy; however, mutations in this gene and the BBS8 gene are thought to play a minor role and mutations in chaperonin-like BBS genes are found to be a major contributor to disease development in a multiethnic Bardet-Biedl syndrome patient population. Two transcript variants encoding distinct isoforms have been identified for this gene.provided by RefSeq, Oct 2014
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Documents
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Other Versions
SKU Description Size Price
KN407504 BBS7 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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